Cannabidiol, also named as CBD, belongs to a large group of cannaboids. Cannabidiol is extracted from industrial hemp plants (Cannabis Sativa L) that also contain many different active substances.
Cannabidiol is obtained through various extraction methods. And has a different effect than delta 9 (THC) where the hemp plant is best known for. But cannanidiol does not contain any psychoactive properties. In recent years, more and more research has been done about Cannabidiol and its special properties.
The endocannaboid system ensures that a correct balance is maintained within the body.
The endocannaboids and their receptors are found in the brain, organs, connective tissue, glands and immune cells. In every piece of tissue the cannaboid system performs certain tasks, but always with the same goal in mind: Homeostasis, maintaining a stable balance in the body, despite the fluctuations on the outside of the body.
Cannaboids promote homeostasis at every level of biological life, from the sub-cells to the organism, and perhaps even the entire communities beyond. To give a good example: Autophagy, that is a process in which a cell sequesters parts of the content in order to digest and recycle itself. This process is effected by the cannabinoid system.
The most common forms of CBD and THC are their acid forms, CBDA and THCA. The raw form of THCA has no psychoactive effect that only happens if the THCA is heated. These cannabinoids are in their acid form is regarded as inactive. CBDA is often forgotten, a little research has been done compared to CBD. The investigations which is sometimes made from concluded that contains the onstekkingsremmende and anti-proliteratieve properties.
CBG called cannabigerol is the precursor of THCA and CBDA. Cannabigerol (CBG) can cause an inhibitory effect on GABA, a substance in the brains of neuron determined how much stimulation is needed to cause a reaction. When GABA inhibited can reduce anxiety and muscle tension, a similar effect of cannabidiol (CBD).
Interview with Dr. Manuel Guzman.
Recorded at the 6th European Endocannabinoid conference in Dublin in 2013.
Dr. Manuel Guzman is a professor of Biochemistry and Molecular Biology at the University of Madrid and told about his research into the medical uses of cannabis.
Manuel Guzmán was born in 1963 in Madrid and obtained his BSc in 1986 and his doctorate in biology in 1990 from the University of Madrid.